The post-pandemic geopolitical dynamics of Southeast Asia have undergone significant changes reflecting new challenges and opportunities for countries in the region. After being hit by COVID-19, Southeast Asia is trying to recover economically and socially, but global power dynamics are also influencing the direction of policies and relations between countries. First, economic recovery is a top priority. Countries such as Indonesia, Malaysia and Thailand face challenges in returning economic growth to a positive track. Efforts to increase foreign direct investment (FDI) are important, with a focus on digitalization and innovation. Additionally, the tourism sector—which has been hit hard by the pandemic—is facing transformation with the implementation of strict health protocols and digital interoperability. Second, the rivalry between the United States and China is intensifying. The United States seeks to strengthen its position through strategic partnerships, such as AUKUS and the Quad involving Australia, India and Japan. This has an impact on strategic defense in Southeast Asia, with countries such as the Philippines and Vietnam increasing defense cooperation to face regional threats. Third, the South China Sea issue remains a point where tensions develop. China continues to expand its power and territorial claims, while ASEAN member countries seek to manage relations with Beijing to maintain regional stability. A multilateral approach through ASEAN is important to defuse conflict and build understanding, although challenges remain. Fourth, climate change and sustainability are becoming an integral part of geopolitics. Countries in Southeast Asia, such as Indonesia and Malaysia, are switching to renewable energy and committing to reducing carbon emissions. Regional cooperation in dealing with natural disasters and water resources management is key to maintaining environmental and economic resilience. Fifth, social issues are also a concern. Inequalities exacerbated by the pandemic are pushing countries to focus more on inclusive development. The government needs to increase access to education, health and technology for society to reduce existing social gaps. Additionally, developments in 5G technology and overall digitalization are accelerating changes in business and communications. Investment in digital infrastructure is very important to support technology-based economic growth and increase competitiveness at the global level. Sixth, political transformation in several countries, such as Myanmar which is facing a post-coup crisis, is changing regional dynamics. The actions of other countries and ASEAN’s attitude towards this crisis will determine regional stability. Diplomacy and active engagement will be key elements in dealing with issues like this. Lastly, the involvement of civil society and social movements in Southeast Asia is increasing. Increased political awareness and demands for government accountability are driving new dynamics in government and public policy. Overall, the geopolitical dynamics of post-pandemic Southeast Asia create a complex landscape. Every country in the region needs to adapt to global and domestic changes to achieve sustainable stability, growth and security.